This page is part of the 10N-Matrix for a high quality conduct of pediatric anesthesia care.
Maintenance of expected arterial carbon dioxide tension.
Blood arterial carbon dioxide tensions are modified during anesthesia. Changes in arterial carbon dioxide tensions significantly affect body homeostasis including the acid-base status, the sympathomimetic tone and organ blood flow.
Acute and chronic changes in arterial carbon dioxide tensions lead to short- and long-term outcomes:
- modulation of vasoreactivity
- central nervous system damage
- neuro-behavioral changes
Prevention and treatment
- aim to achieve adequate carbon dioxide tensions
- acute changes in carbon dioxide tensions are commonly a result of difficulties and critical incidences during airway and ventilation management.
- regular teaching and training of ventilation strategies
- consider limitations of monitoring and airway equipment
- use cuffed endotracheal tubes if appropriate
- recognize discrepancies between arterial and end-tidal carbon dioxide tensions
- Establish regulation for delivery of adequate ventilation management
- Avoid acute high amplitude fluctuations of arterial carbon dioxide tension
- Ringer SK, Clausen NG, Spielmann N, Weiss M. Effects of moderate and severe hypocapnia on intracerebral perfusion and brain tissue oxygenation in piglets. Paediatr Anaesth. 2019 Nov;29(11):1114-1121
- Rhondali O, Juhel S, Mathews S, Cellier Q, Desgranges FP, Mahr A, De Queiroz M, Pouyau A, Rhzioual-Berrada K, Chassard D. Impact of sevoflurane anesthesia on brain oxygenation in children younger than 2 years. Paediatr Anaesth. 2014 Jul;24(7):734-40.
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- Normal Heart Rate
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