Selected Publications

Clausen NG, Antonsen S, Spielmann N, Hansen TG, Weiss M, Ringer SK.
Hypotension and Hypocapnia During General Anesthesia in Piglets: Study of S100b as an Acute Biomarker for Cerebral Tissue Injury
J Neurosurg Anesthesiol. 2019 Apr 23.

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Ringer SK, Clausen NG, Spielmann N, Ohlerth S, Schwarz A, Weiss M.
Effects of moderate and severe arterial hypotension on intracerebral perfusion and brain tissue oxygenation in piglets.
Br J Anaesth. 2018 Dec;121(6):1308-1315

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Raviraj D, Engelhardt T, Giedsing Hansen T.
Safe anesthesia for neonates, infants and children.
Minerva Pediatr. 2018 Oct;70(5):458-466.

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Disma N, O’Leary JD, Loepke AW, Brambrink AM, Becke K, Clausen NG, De Graaff JC, Liu F, Hansen TG, McCann ME, Salorio CF, Soriano S, Sun LS, Szmuk P, Warner DO, Vutskits L, Davidson AJ.
Anesthesia and the developing brain: A way forward for laboratory and clinical research.
Paediatr Anaesth. 2018 Sep;28(9):758-763.

Engelhardt T, Virag K, Veyckemans F, Habre W; APRICOT Group of the European Society of Anaesthesiology Clinical Trial Network.
Airway management in paediatric anaesthesia in Europe-insights from APRICOT (Anaesthesia Practice In Children Observational Trial): a prospective multicentre observational study in 261 hospitals in Europe.
Br J Anaesth. 2018 Jul;121(1):66-75

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Hansen TG, Engelhardt T.
Long-term neurocognitive outcomes following surgery and anaesthesia in early life.
Curr Opin Anaesthesiol. 2018 Jun;31(3):297-301..

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Burton ZA, Woodman N, Harclerode Z, Engelhardt T; PATRN Committee.
Drug errors in paediatric anaesthesia are common-but often unreported unless actual harm occurs.
Br J Anaesth. 2018 Mar;120(3):600-601.

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Dokkedal U, Wod M, Thinggaard M, Hansen TG, Rasmussen LS, Mengel-From J, Christensen K.
No impact of surgery on cognitive function: a longitudinal study of middle-aged Danish twins.
Ann Epidemiol. 2018;28(2):95-101

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de Graaff JC, Engelhardt T
How big data shape paediatric anaesthesia.
Br J Anaesth 2017; 119:448-451.

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Hansen TG
Use of anesthetics in young children: Consensus statement of the European Society of Anaesthesiology (ESA),  the European Society for Paediatric Anaesthesiology (ESPA), the European Association of Cardiothoracic Anaesthesiology (EACTA),  and the European Safe Tots Anaesthesia Research Initiative (EuroSTAR).
Paediatr Anaesth. 2017; 27: 558-9.

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Hansen TG
Use of anaesthetics in young children: Consensus statement of the European Society of Anaesthesiology,  the European Society for Paediatric Anaesthesiology, the European Association of Cardiothoracic Anaesthesiology  and the European Safe Tots Anaesthesia Research Initiative.
Eur J Anaesthesiol. 2017; 34: 327-8.

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Becke K, Höhne C, Eich C, Engelhardt T, Hansen T, Weiss M
Kinderanästhesie: Was wirklich wichtig ist [Paediatric Anaesthesia: What really matters].
Dtsch Arztebl 2017; 114(4): A-166 / B-148 / C-148

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Davidson A, Vutskits L
The new FDA drug safety communication on the use of general anesthetics in young children: what should we make of it?
Paediatr Anaesth. 2017; 27: 336-7.

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Habre W, Disma N, Virag K, Becke K, Hansen TG, Jöhr M, Leva B, Morton NS, Vermeulen PM,  Zielinska M, Boda K, Veyckemans F;  APRICOT Group of the European Society of Anaesthesiology Clinical Trial Network
Incidence of severe critical events in paediatric anaesthesia (APRICOT):  a prospective multicentre observational study in 261 hospitals in Europe.
Lancet Respir Med. 2017; 5: 412-25.

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Clausen NG, Pedersen DA, Pedersen JK, Møller SE, Grosen D, Wehby GL, Christensen K, Hansen TG.
Oral Clefts and Academic Performance in Adolescence: The Impact of Anesthesia-Related Neurotoxicity, Timing of Surgery, and Type of Oral Clefts.
Cleft Palate Craniofac J. 2017; 54(4):371-380.

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Hansen TG, Engelhardt T, Weiss M
The Relevance of Anesthetic Drug-Induced Neurotoxicity.
JAMA Pediatr. 2017; 171: e163481.

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Ringer SK, Ohlerth S, Carrera I, Mauch J, Spielmann N, Bettschart-Wolfensberger R, Weiss M
Effects of hypotension and/or hypocapnia during sevoflurane anesthesia on perfusion and metabolites in the developing brain of piglets- a blinded randomized study.
Paediatr Anaesth. 2016; 26: 909-18.

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Vutskits L, Xie Z.
Lasting impact of general anaesthesia on the brain: mechanisms and relevance.
Nat Rev Neurosci. 2016 Oct 18;17(11):705-717.

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Disma N, Hansen TG.
Pediatric anesthesia and neurotoxicity: can findings be translated from animals to humans?
Minerva Anestesiol. 2016; 82(7):791-6

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Weiss M, Hansen TG, Engelhardt T
Ensuring safe anaesthesia for neonates, infants and young children: what really matters.
Arch Dis Child. 2016; 101: 650-2.

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Weiss M, Becke K, Hansen TG, Engelhardt T
The GAS trial.
Lancet. 2016; 387: 1614.

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Djurhuus BD, Hansen TG, Pedersen JK, Faber CE, Christensen K.
School performance in cholesteatoma-operated children in Denmark: a nationwide population-based register-study.
Acta Otolaryngol. 2016; 136(7):663-8.

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Hansen TG, Lönnqvist PA
The rise and fall of anaesthesia-related neurotoxicity and the immature developing human brain.
Acta Anaesthesiol Scand. 2016; 60: 280-3.

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Koch HW, Hansen TG.
Perioperative use of cerebral and renal near-infrared spectroscopy in neonates: a 24-h observational study.
Paediatr Anaesth. 2016; 26(2):190-8.

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Ibrahim RM, Krammer CW, Hansen TG, Kristensen BW, Vutskits L, Sørensen JA.
Systemic physiology and neuroapoptotic profiles in young and adult rats exposed to surgery: A randomized controlled study comprising four different anaesthetic techniques.
Int J Dev Neurosci. 2015; 45:11-8.

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Loepke AW, Hansen TG.
Is this your (paediatric patient’s) brain on (anaesthetic) drugs?: The search for a potential neurological phenotype of anaesthesia-related neurotoxicity in humans.
Eur J Anaesthesiol. 2015; 32(5):298-300.

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Hansen TG.
Effects of anesthesia on the developing brain: can the underlying disease be ignored?
Paediatr Anaesth. 2015; 25(4):436-7.

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Weiss M, Vutskits L, Hansen TG, Engelhardt T
Safe Anesthesia For Every Tot – The SAFETOTS initiative.
Curr Opin in Anaesthesiol. 2015; 28: 302-7.

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Hansen TG, Pedersen JK, Henneberg SW, Morton NS, Christensen K.
Neurosurgical conditions and procedures in infancy are associated with mortality and academic performances in adolescence: a nationwide cohort study.
Paediatr Anaesth. 2015;25(2):186-92.

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Weiss M, Bissonnette B, Engelhardt T, Soriano S
Anesthetists rather than anesthetics are the threat to baby brains.
Paediatr Anaesth. 2013; 23: 881-2.

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McCann ME, Soriano SG
Perioperative central nervous system injury in neonates.
Br J Anaesth. 2012; 109 Suppl 1:i60-7.

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